Understanding the Biology of Human Interstitial Cells of Cajal in Gastrointestinal Motility
نویسندگان
چکیده
منابع مشابه
Do we need to revise the role of interstitial cells of Cajal in gastrointestinal motility?
AS ITS NAME SUGGESTS, the tunica muscularis of the gastrointestinal tract is dominated by smooth muscle cells, which perform all the mechanical work required for digestion, absorption, and waste removal. The muscle layers also contain several other cell types, which, despite representing a much smaller percentage of the total cellular content, also contribute to gastrointestinal motility by reg...
متن کاملRoles of interstitial cells of Cajal in regulating gastrointestinal motility: in vitro versus in vivo studies
The aim of this article is to provide a better understanding of the roles of interstitial cells of Cajal (ICC) in regulating gastrointestinal motility by reviewing in vitro and in vivo physiological motility studies. Based on the in vitro studies, ICC are proposed to have the following functions: to generate slow waves, to mediate neurotransmission between the enteric nerves and the gastrointes...
متن کاملthe relationship between intestinal motility and interstitial cells of cajal in nonalcoholic fatty liver mice
background nonalcoholic fatty liver disease (nafld) is the most common cause of chronic liver disease in western world. however, nafld shows an increasing trend in china every year, which has attracted the attention of national health authorities. the previous studies have shown that nafld caused severe gastrointestinal motor disorders, but little is known about the interstitial cells of cajal ...
متن کاملGastrointestinal Stromal Tumors, Interstitial Cells of Cajal and their Nomenclature
Currently, gastrointestinal stromal tumors (GIST) have been emphasized considerably in the literature. Following the date of the description of interstitial cells of Cajal (ICC) by Santiago Ramon y Cajal in the late 19th century, this issue has been very popular. Lately, discovery of the association of GISTs with c-Kit mutations in their development, and the significance of drugs such as imatin...
متن کاملThe Role of Interstitial Cells of Cajal (ICC) in Gastrointestinal Motility Disorders – What the Gastroenterologist Has to Know
Undisturbed gastrointestinal motility or peristalsis is critical for effective digestion and absorption of our food and its ingredients. Peristaltic waves in the gut are propelled by the circular and longitudinal layers of smooth muscle cells in the different segments of the gastrointestinal tract. The initiation and regulation of peristalsis is a complex process which, secondary to smooth musc...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21124540